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Reducing the Impact of Infectious Diseases by Supporting Trans-Disciplinary Academic Research

3 Cavaliers

Supported by a university-wide faculty expertise database, 3 Cavaliers facilitates funding for faculty members from at least two disparate disciplines, located in different units or schools. The platform helps faculty members self-assemble and pursue new research projects that may not be ready for external funding or may not fit traditional funding models. GIDI contributed seed funds to the 3C program to further support infectious disease research. In total, GIDI contributed $40k across three projects. The three projects are described here:

The Impact of the Affordable Care Act's Dependent Mandate on People Living with HIV  This project will use econometrics methods to investigate the effects of the Affordable Care Act’s dependent mandate on HIV viral suppression for people living with HIV ages 23-28 in Virginia.

Research Participants: Daniel Sebastian Tello-Trillo, PhD - Frank Batten School , Jessica Keim Malpass, PhD - Nursing, Rebecca A. Dillingham, PhD - Infectious Diseases

Extracellular Life Style of an Intracellular Pathogen We will test the hypothesis that before reaching the colon where it is an intracellular pathogen, S. flexneri develops an extracellular life style relying on biofilm formation in the small intestine.

Research Participants: Herve F. Agaisse, PhD - Microbiology , Andreas Gahlmann, PhD - Chemistry , Huiwang Ai, PhD - Molecular Physics & Biophysics

Development of Antibiotic Resistance "In the Wild" The study of emergence of antibiotic resistance in real-life by modeling complex microbial communities, characterizing resistance in wastewater treatment, and simulating drug-protein interactions.

Research Participants: Jason A. Papin, PhD - Biomedical Engineering, SOM, Lisa Colosi Peterson, PhD - Civil & Environmental Engineering , Peter M. Kasson, PhD - Molecular Physics & Biophysics